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Association of gene variants with juvenile amyotrophic lateral sclerosis

Frontiers of Medicine doi: 10.1007/s11684-023-1005-y

Abstract: A variation within <i>TRMT2Bi> (c.1356G>T; p.K452N) was identified to be associated with ALS in a familya high level of ROS were observed functionally in patient-originated lymphoblastoid cell lines and <i>TRMT2Bi> interfering HEK293 cells.Further, <i>TRMT2Bi> variations overexpression cells also displayed decreased ND1.In conclusion, a novel JALS-associated gene called <i>TRMT2Bi> was identified, thus broadening the

Keywords： <i>TRMT2Bi>     amyotrophic lateral sclerosis     mitochondrial complex I     tRNA methylation     reactive oxygen    

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Anti-β glycoprotein I antibodies in complex with β2 glycoprotein I induce platelet activation via tworeceptors: apolipoprotein E receptor 2' and glycoprotein I bα

Wenjing Zhang,Fei Gao,Donghe Lu,Na Sun,Xiaoxue Yin,Meili Jin,Yanhong Liu

Frontiers of Medicine 2016, Volume 10, Issue 1,   Pages 76-84 doi: 10.1007/s11684-015-0426-7

Abstract:

Anti-β2 glycoprotein I (anti-β2GP I ) antibodies are importantba (GP I bα) in platelet activation induced by the anti-β2GP I /β2B2 production as well as p38 mitogen-activated protein kinase phosphorylationactivate platelets, and this activation was inhibited by either the anti-GP I bα antibody or theactivation via GP I bα and apoER2', which may then contribute to the prothrombotic tendency

Keywords： anti-β2GP I /β2GP I complex     platelet     GP I bα     apoER2'     thrombosis    

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supported polyhedral NiS/NiS nanocrystals with excellent photocatalytic performance for removing rhodamine B

Frontiers of Chemical Science and Engineering 2021, Volume 15, Issue 6,   Pages 1537-1549 doi: 10.1007/s11705-021-2094-2

Abstract: Hence, photoreduction of Cr(VI) to Cr(III) and degradation of rhodamine B (RhB) using a novel photocatalystIn this work, <i>hi>-BN/NiS2/NiS composites were prepared via a simple solvothermal methodThe 7 wt-% <i>hi>-BN/NiS2/NiS composites were characterized via a larger specific surfaceHowever, the removal rate of RhB by the 7 wt-% <i>hi>-BN/NiS2/NiS photocatalyst reachedhi>-BN promoted transportation of photoinduced charges on the surface of the <i>hi>-BN/NiS2<

Keywords： graphene-like <i>hi>-BN     <i>hi>-BN/NiS2/NiS composites     photocatalysis     Cr(VI) reduction    

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MicroRNA-148b promotes proliferation of hair follicle cells by targeting

Wanbao YANG,Qinqun LI,Bo SU,Mei YU

Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 1,   Pages 72-80 doi: 10.15302/J-FASE-2016089

Abstract: In our study, we found by qRT-PCR that miR-148b was significantly upregulated in sheep wool follicleOverexpression of miR-148b promoted proliferation of both HHDPC and HHGMC.By using the TOPFlash system we demonstrated that miR-148b could activate Wnt/β-catenin pathway andfactor nuclear factor of activated T cells type 5 ( ) and were predicted to be the target of miR-148bSubsequently was further identified as the target of miR-148b using western blotting.

Keywords： miR-148b     hair follicle     proliferation     <i>NFAT5i>     <i>Wnt10bi>    

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Inhibition of NO emission by adding antioxidant mixture in

B. ANAND

Frontiers in Energy 2015, Volume 9, Issue 2,   Pages 238-245 doi: 10.1007/s11708-015-0356-8

Abstract: In this paper, the effect of adding an antioxidant mixture in biodiesel as fuel, in a single cylinder, direct injection compression ignition engine was experimentally investigated and the level of pollutants in the exhaust and performance characteristics of the engine were analyzed. Nine test fuels were prepared with three antioxidants, namely, Succinimide (C H NO ), , dimethyl- -phenylenediamine-dihydrochloride (C H Cl N ), and -phenyl- -phenylenediamine (C H NHC H NH ) added to neat biodiesel at 500 parts per million (ppm), 1000 ppm and 2000 ppm and the observed experimental results were compared with those of neat biodiesel and neat diesel as base fuels. The comparison showed that NO emission was reduced drastically for the test fuels with the antioxidant addition of 2000 ppm. The maximum reduction of 10% of NO emission was observed for the antioxidant mixture in neat biodiesel, with a slight increase in unburned HC, CO and smoke opacity. In addition, the obtained experimental results reveal that the addition of two antioxidants as mixture in neat biodiesel caused improved NO emission reduction for all test fuels.

Keywords： NO emission     antioxidants     Succinimide     <i>Ni>     <i>Ni>-dimethyl-<i>pi>-phenylenediamine-dihydrochloride     <i>Ni>-phenyl-<i>pi>-phenylenediamine    

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Thermal and Mechanical Properties Optimization of <i>ABi>O4 Type EuNbO4 By the<i>Bi>-Site Substitution of Ta Article

Lin Chen, Jing Feng

Engineering 2020, Volume 6, Issue 2,   Pages 177-184 doi: 10.1016/j.eng.2019.12.006

Abstract: In this work, B-site substitution of tantalum (Ta) is used to optimize the thermal and mechanicalthat the thermal and mechanical properties of EuNbO4 can be effectually optimized via the B-site

Keywords： Thermal barrier coatings     Rare earth niobates     Substitution     Thermal conductivity     Thermal expansion coefficients     Young’s modulus    

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SARS-CoV-2 Entry Factors: <i>ACE2i> and <i>TMPRSS2i> Are Expressed in Peri-Implantation Embryos and Article

Wei Chen, Peng Yuan, Ming Yang, Zhiqiang Yan, Siming Kong, Jie Yan, Xixi Liu, Yidong Chen, Jie Qiao, Liying Yan

Engineering 2020, Volume 6, Issue 10,   Pages 1162-1169 doi: 10.1016/j.eng.2020.07.013

Abstract:

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread throughout the world, leadingAngiotensin-converting enzyme 2 (ACE2) is the receptor of both severe acute respiratory syndrome coronavirus(SARS-CoV) and SARS-CoV-2.In order to investigate the potential risk of SARS-CoV-2 vertical transmission, we explored ACE2/em> and TMPRSS2, indicating SARS-CoV-2 infection susceptibility.

Keywords： SARS-CoV-2     ACE2     Vertical transmission     Placenta     Peri-implantation    

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Phytotoxicity in seven higher plant species exposed to di-

Tingting MA,Ying TENG,Peter CHRISTIE,Yongming LUO

Frontiers of Environmental Science & Engineering 2015, Volume 9, Issue 2,   Pages 259-268 doi: 10.1007/s11783-014-0652-2

Abstract: species exposed to a range of concentrations (0– 500 mg·kg soil) of di- -butyl phthalate (DnBP) or bis (2-( L.), oat ( ) and onion ( L.), together with monitoring of plant pigment content (chlorophyll a, bto the photosynthetic system of test plants, mainly by decreasing the content of chlorophyll a and b.

Keywords： phytotoxicity     di-<i>ni>-butyl phthalate     bis(2-ethylhexyl) phthalate     malondialdehyde     plant pigments(chlorophyll a     b and carotinoids)    

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Elasto-plastic fatigue crack growth analysis of plane problems in the presence of flaws using XFEM

SHEDBALE,I. V. SINGH,B. K. MISHRA

Frontiers of Structural and Civil Engineering 2015, Volume 9, Issue 4,   Pages 420-440 doi: 10.1007/s11709-015-0305-y

Abstract: The -integral for two fracture modes (mode-I and mode-II) is obtained by decomposing the displacement

Keywords： XFEM     von-Mises yield criterion     isotropic hardening     fatigue crack growth     <i>Ji>-integral    

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<i>RR1i> and <i>RR2i> gene deletion affects the immunogenicity of a live attenuated pseudorabies

Shijun YAN,He YAN,Chaolin ZHANG,Tongyan WANG,Qingyuan YANG,Zhe SUN,Yan XIAO,Feifei TAN,Xiangdong LI,Kegong TIAN

Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 1,   Pages 81-86 doi: 10.15302/J-FASE-2016088

Abstract: As virulence-determining genes, and encode the small subunit and large subunit of viral ribonucleotide reductase (RR) in pseudorabies virus which have been extensively studied in mice. However, their role in pigs has not been adequately investigated. In this study, we deleted and genes based on a / / triple gene-deleted pseudorabies virus and tested its efficacy in pigs as a vaccine candidate. The rescued virus showed similar growth properties and plaque size as its parent strain. In an animal study, the virus could elicit humoral immune responses shown by generation of gB-specific antibodies and virus neutralizing antibodies. However, vaccination could not provide protection against virulent pseudorabies virus challenge since vaccinated pigs showed clinical pseudorabies-specific syndromes. The deficiency in protection may due to the generation of late and low levels of gB antibodies and virus neutralizing antibodies.

Keywords： pseudorabies virus     <i>RR1i> and <i>RR2i>     ribonucleotide reductase     vaccine candidate    

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NiBO (B = Mn or Co) catalysts for NH-SCR of NO at low-temperature in microwave field

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 8, doi: 10.1007/s11783-023-1696-y

Abstract:

● Microwave-assisted catalytic NH3-SCR reaction over spinel oxides is carried out.

Keywords： Microwave field     Spinel oxides     NO<i>xi>     Selective catalytic reduction    

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Evaluation of H2 on the Evolution Mechanism of NO<i>xi> Storage and Reductionover Pt–Ba–Ce/γ-Al2O3 Catalysts Article

Pan Wang, Jing Yi, Chuan Sun, Peng Luo, Lili Lei

Engineering 2019, Volume 5, Issue 3,   Pages 568-575 doi: 10.1016/j.eng.2019.02.005

Abstract:

In this investigation, Pt–Ba–Ce/γ-Al2O3 catalysts were preparedby incipient wetness impregnation and experiments were performed to evaluate the influence of H2 onThe physical and chemical properties of the Pt–Ba–Ce/γ-Al2O3sub>, whose peaks were observed in X-ray diffraction (XRD) spectra, dispersed well on the γ-Al2O3/sub> exposure (i.e., 30 s, 45 s, and 60 s) was extended.

Keywords： Pt–Ba–Ce/γ-Al2O3 catalysts     Physicochemical properties     NO<i>xi> storageand reduction     NO<i>xi> emission     H2 reductant    

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<i>Ni>-Positive ion activated rapid addition and mitochondrial targeting ratiometric fluorescent probesfor <i>in vivoi> cell H2S imaging

Yan Shi, Fangjun Huo, Yongkang Yue, Caixia Yin

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 1,   Pages 64-71 doi: 10.1007/s11705-021-2048-8

Abstract: Heterocyclic compound quinoline and its derivatives exist in natural compounds and have a broad spectrum of biological activity. They play an important role in the design of new structural entities for medical applications. Similarly, indoles and their derivatives are found widely in nature. Amino acids, alkaloids and auxin are all derivatives of indoles, as are dyes, and their condensation with aldehydes makes it easy to construct reaction sites for nucleophilic addition agents. In this work, we combine these two groups organically to construct a rapid response site (within 30 s) for H S, and at the same time, a ratiometric fluorescence response is presented throughout the process of H S detection. As such, the lower detection limit can reach 55.7 nmol/L for H S. In addition, cell imaging shows that this probe can be used for the mitochondrial targeted detection of endogenous and exogenous H S. Finally, this probe application was verified by imaging H S in nude mice.

Keywords： heterocyclic compound     hydrogen sulfide     ratiometric     mitochondrial targeted    

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NO<i>xi> and H2S formation in the reductive zone of air-staged combustion of

Jinzhi CAI, Dan LI, Denggao CHEN, Zhenshan LI

Frontiers in Energy 2021, Volume 15, Issue 1,   Pages 4-13 doi: 10.1007/s11708-020-0804-y

Abstract: Low NO combustion of blended coals is widely used in coal-fired boilers in China to control NO emission; thus, it is necessary to understand the formation mechanism of NO and H S during the combustion of blended coals. This paper focused on the investigation of reductive gases in the formation of NO and H S in the reductive zone of blended coals during combustion. Experiments with Zhundong (ZD) and Commercial (GE) coal and their blends with different mixing ratios were conducted in a drop tube furnace at 1200°C–1400°C with an excessive air ratio of 0.6–1.2. The coal conversion and formation characteristics of CO, H S, and NO in the fuel-rich zone were carefully studied under different experimental conditions for different blend ratios. Blending ZD into GE was found to increase not only the coal conversion but also the concentrations of CO and H S as NO reduction accelerated. Both the CO and H S concentrations inblended coal combustion increase with an increase in the combustion temperature and a decrease in the excessive air ratio. Based on accumulated experimental data, one interesting finding was that NO and H S from blended coal combustion were almost directly dependent on the CO concentration, and the CO concentration of the blended coal combustion depended on the single char gasification conversion.Thus, CO, NO , and H S formation characteristics from blended coal combustion can be well predicted by single char gasification kinetics.

Keywords： blended coal combustion     NO<i>x i>formation     H2S formation     air staged combustion    

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Trihydrazinotriazine-grafting Fe

Jamal Rahimi, Seyedeh Shadi Mirmohammadi, Ali Maleki

Frontiers of Chemical Science and Engineering 2021, Volume 15, Issue 4,   Pages 1008-1020 doi: 10.1007/s11705-020-1996-8

Abstract: This study focuses on the synthesis and characterization of a novel magnetic nanocomposite 2,4,6-trihydrazino

Keywords： trihydrazino-triazine     porous     magnetic nanocatalyst     green chemistry     tetrahydrobenzo[<i>bi>]pyrans    

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Title Author Date Type Operation

Association of gene variants with juvenile amyotrophic lateral sclerosis

Journal Article

Anti-β glycoprotein I antibodies in complex with β2 glycoprotein I induce platelet activation via tworeceptors: apolipoprotein E receptor 2' and glycoprotein I bα

Wenjing Zhang,Fei Gao,Donghe Lu,Na Sun,Xiaoxue Yin,Meili Jin,Yanhong Liu

Journal Article

supported polyhedral NiS/NiS nanocrystals with excellent photocatalytic performance for removing rhodamine B

Journal Article

MicroRNA-148b promotes proliferation of hair follicle cells by targeting

Wanbao YANG,Qinqun LI,Bo SU,Mei YU

Journal Article

Inhibition of NO emission by adding antioxidant mixture in

B. ANAND

Journal Article

Thermal and Mechanical Properties Optimization of <i>ABi>O4 Type EuNbO4 By the<i>Bi>-Site Substitution of Ta

Lin Chen, Jing Feng

Journal Article

SARS-CoV-2 Entry Factors: <i>ACE2i> and <i>TMPRSS2i> Are Expressed in Peri-Implantation Embryos and

Wei Chen, Peng Yuan, Ming Yang, Zhiqiang Yan, Siming Kong, Jie Yan, Xixi Liu, Yidong Chen, Jie Qiao, Liying Yan

Journal Article

Phytotoxicity in seven higher plant species exposed to di-

Tingting MA,Ying TENG,Peter CHRISTIE,Yongming LUO

Journal Article

Elasto-plastic fatigue crack growth analysis of plane problems in the presence of flaws using XFEM

SHEDBALE,I. V. SINGH,B. K. MISHRA

Journal Article

<i>RR1i> and <i>RR2i> gene deletion affects the immunogenicity of a live attenuated pseudorabies

Shijun YAN,He YAN,Chaolin ZHANG,Tongyan WANG,Qingyuan YANG,Zhe SUN,Yan XIAO,Feifei TAN,Xiangdong LI,Kegong TIAN

Journal Article

NiBO (B = Mn or Co) catalysts for NH-SCR of NO at low-temperature in microwave field

Journal Article

Evaluation of H2 on the Evolution Mechanism of NO<i>xi> Storage and Reductionover Pt–Ba–Ce/γ-Al2O3 Catalysts

Pan Wang, Jing Yi, Chuan Sun, Peng Luo, Lili Lei

Journal Article

<i>Ni>-Positive ion activated rapid addition and mitochondrial targeting ratiometric fluorescent probesfor <i>in vivoi> cell H2S imaging

Yan Shi, Fangjun Huo, Yongkang Yue, Caixia Yin

Journal Article

NO<i>xi> and H2S formation in the reductive zone of air-staged combustion of

Jinzhi CAI, Dan LI, Denggao CHEN, Zhenshan LI

Journal Article

Trihydrazinotriazine-grafting Fe

Jamal Rahimi, Seyedeh Shadi Mirmohammadi, Ali Maleki

Journal Article